Sorrento Therapeutics, Inc., a clinical stage Biopharma company, develops treatments for cancer, autoimmune, inflammatory and neurodegenerative diseases. She operates in two segments – Sorrento Therapeutics and Scilex. The company provides cancer therapists through the use of a proprietary r-monoclonal antibody antibody library and targeted delivery conditions that include chimeric antigen receptor T-cell therapy (car-T), dimeric antigen receptor T-cell therapy, and antibody-drug conjugates as well as bispecific antibody approaches. It also offers Sofusa, a drug delivery technology that delivers biological substances directly to the lymphatic system. In addition, the company’s clinical programs include anti-CD38 CAR-T therapy for the treatment of multiple myeloma as well as amyloidosis and graft versus host diseases. In addition, he is developing resiniferatoxin, a neopioid-based TRPV1 agonist neurotoxin for the treatment of advanced cancer and osteoarthritis of knee pain; and ZTlido, a lidocaine delivery system for the treatment of postherpetic neuralgia. In addition, the company is developing SEMDEXA, an injectable viscous gel formulation that is a Phase III trial for the treatment of sciatica, a pathology of low back pain; and SP-103, an investigational non-aqueous lidocaine topical system in clinical development for chronic low back pain. She has various collaborations with SmartPharm Therapeutics Inc. to develop a gene-encoded vaccine antibody to protect against COVID-19; Celularity, Inc. to initiate a Phase I / II clinical trial with up to 86 COVID-19 patients; and the Mount Sinai Health System to develop COVI-SHIELD, an antibody therapy targeting SARS-CoV-2 infection, and a Research Trials Agreement with the University of Texas Medical Branch at Galveston for preclinical testing of Sorrento’s COVID-19 therapeutic product candidates. The company was founded in 2006 and is based in San Diego, California.
